1ywi
From Proteopedia
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| - | [[Image:1ywi.jpg|left|200px]] | + | [[Image:1ywi.jpg|left|200px]] |
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| - | '''Structure of the FBP11WW1 domain complexed to the peptide APPTPPPLPP''' | + | {{Structure |
| + | |PDB= 1ywi |SIZE=350|CAPTION= <scene name='initialview01'>1ywi</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''Structure of the FBP11WW1 domain complexed to the peptide APPTPPPLPP''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1YWI is a [ | + | 1YWI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YWI OCA]. |
==Reference== | ==Reference== | ||
| - | Structural basis for APPTPPPLPP peptide recognition by the FBP11WW1 domain., Pires JR, Parthier C, Aido-Machado R, Wiedemann U, Otte L, Bohm G, Rudolph R, Oschkinat H, J Mol Biol. 2005 Apr 29;348(2):399-408. PMID:[http:// | + | Structural basis for APPTPPPLPP peptide recognition by the FBP11WW1 domain., Pires JR, Parthier C, Aido-Machado R, Wiedemann U, Otte L, Bohm G, Rudolph R, Oschkinat H, J Mol Biol. 2005 Apr 29;348(2):399-408. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15811376 15811376] |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: Wiedemann, U.]] | [[Category: Wiedemann, U.]] | ||
[[Category: class ii]] | [[Category: class ii]] | ||
| - | [[Category: proline-rich | + | [[Category: proline-rich peptide]] |
| - | [[Category: protein-protein | + | [[Category: protein-protein interaction]] |
[[Category: ww domain]] | [[Category: ww domain]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:28:26 2008'' |
Revision as of 13:28, 20 March 2008
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
Structure of the FBP11WW1 domain complexed to the peptide APPTPPPLPP
Overview
WW domains are small protein-protein interaction modules that recognize proline-rich stretches in proteins. The class II tandem WW domains of the formin binding protein 11 (FBP11) recognize specifically proteins containing PPLPp motifs as present in the formins that are involved in limb and kidney development, and in the methyl-CpG-binding protein 2 (MeCP2), associated with the Rett syndrome. The interaction involves the specific recognition of a leucine side-chain. Here, we report on the novel structure of the complex formed by the FPB11WW1 domain and the formin fragment APPTPPPLPP revealing the specificity determinants of class II WW domains.
About this Structure
1YWI is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structural basis for APPTPPPLPP peptide recognition by the FBP11WW1 domain., Pires JR, Parthier C, Aido-Machado R, Wiedemann U, Otte L, Bohm G, Rudolph R, Oschkinat H, J Mol Biol. 2005 Apr 29;348(2):399-408. PMID:15811376
Page seeded by OCA on Thu Mar 20 15:28:26 2008
