3j6l

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<StructureSection load='3j6l' size='340' side='right' caption='[[3j6l]], [[Resolution|resolution]] 9.00&Aring;' scene=''>
<StructureSection load='3j6l' size='340' side='right' caption='[[3j6l]], [[Resolution|resolution]] 9.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3j6l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J6L OCA]. <br>
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<table><tr><td colspan='2'>[[3j6l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J6L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J6L FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3j6m|3j6m]], [[3j6n|3j6n]], [[3j6o|3j6o]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3j6m|3j6m]], [[3j6n|3j6n]], [[3j6o|3j6o]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CXADR, CAR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CXADR, CAR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j6l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j6l RCSB], [http://www.ebi.ac.uk/pdbsum/3j6l PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j6l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j6l RCSB], [http://www.ebi.ac.uk/pdbsum/3j6l PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CXAR_HUMAN CXAR_HUMAN]] Component of the epithelial apical junction complex that is essential for the tight junction integrity. Proposed to function as a homophilic cell adhesion molecule. Recruits MPDZ to intercellular contact sites. Probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN) through adhesive interactions with AMICA1/JAML located in the plasma membrane of PMN.<ref>PMID:9096397</ref> <ref>PMID:11734628</ref> <ref>PMID:12297051</ref> <ref>PMID:15800062</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Kinetic and structural analysis of coxsackievirus B3 receptor interactions and formation of the A-particle.,Organtini LJ, Makhov AM, Conway JF, Hafenstein S, Carson SD J Virol. 2014 Mar 12. PMID:24623425<ref>PMID:24623425</ref>
Kinetic and structural analysis of coxsackievirus B3 receptor interactions and formation of the A-particle.,Organtini LJ, Makhov AM, Conway JF, Hafenstein S, Carson SD J Virol. 2014 Mar 12. PMID:24623425<ref>PMID:24623425</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Carson, S D.]]
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[[Category: Carson, S D]]
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[[Category: Conway, J F.]]
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[[Category: Conway, J F]]
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[[Category: Hafenstein, S.]]
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[[Category: Hafenstein, S]]
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[[Category: Makhov, A M.]]
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[[Category: Makhov, A M]]
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[[Category: Organtini, L J.]]
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[[Category: Organtini, L J]]
[[Category: Car]]
[[Category: Car]]
[[Category: Cell adhesion]]
[[Category: Cell adhesion]]
[[Category: Coxsackievirus b3]]
[[Category: Coxsackievirus b3]]
[[Category: Cvb3]]
[[Category: Cvb3]]

Revision as of 18:55, 24 December 2014

Kinetic and Structural Analysis of Coxsackievirus B3 Receptor Interactions and Formation of the A-particle

3j6l, resolution 9.00Å

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