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4qu7

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4qu7]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QU7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QU7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4qu7]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QU7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QU7 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qu7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qu7 RCSB], [http://www.ebi.ac.uk/pdbsum/4qu7 PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qu7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qu7 RCSB], [http://www.ebi.ac.uk/pdbsum/4qu7 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GRSF1_HUMAN GRSF1_HUMAN]] Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs containing the 14 base G-rich element. Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences.<ref>PMID:23473033</ref> <ref>PMID:23473034</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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[[Category: Structural genomic]]
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[[Category: TCELL, Partnership for T-Cell Biology.]]
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[[Category: TCELL, Partnership for T-Cell Biology]]
[[Category: Canonical rna binding domain]]
[[Category: Canonical rna binding domain]]
[[Category: Jcsg]]
[[Category: Jcsg]]
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[[Category: Joint center for structural genomic]]
 
[[Category: Pf14259]]
[[Category: Pf14259]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
[[Category: Psi-biology]]
[[Category: Psi-biology]]
[[Category: Rna binding protein-rna complex]]
[[Category: Rna binding protein-rna complex]]
[[Category: Rna-binding protein]]
[[Category: Rna-binding protein]]
[[Category: Rrm_6]]
[[Category: Rrm_6]]
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[[Category: Structural genomic]]
 

Revision as of 18:58, 24 December 2014

Crystal structure of a G-rich RNA sequence binding factor 1 (GRSF1) from Homo sapiens at 2.50 A resolution

4qu7, resolution 2.50Å

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