4jqo

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{{STRUCTURE_4jqo| PDB=4jqo | SCENE= }}
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==Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with citrulline and inorganic phosphate==
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===Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with citrulline and inorganic phosphate===
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<StructureSection load='4jqo' size='340' side='right' caption='[[4jqo]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4jqo]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_vulnificus_cmcp6 Vibrio vulnificus cmcp6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JQO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4h31|4h31]], [[4jfr|4jfr]], [[4jhx|4jhx]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">argF, VV1_1466 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216895 Vibrio vulnificus CMCP6])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ornithine_carbamoyltransferase Ornithine carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.3 2.1.3.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jqo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jqo RCSB], [http://www.ebi.ac.uk/pdbsum/4jqo PDBsum]</span></td></tr>
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</table>
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== Function ==
[[http://www.uniprot.org/uniprot/OTC_VIBVU OTC_VIBVU]] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).
[[http://www.uniprot.org/uniprot/OTC_VIBVU OTC_VIBVU]] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).
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==About this Structure==
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==See Also==
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[[4jqo]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_vulnificus_cmcp6 Vibrio vulnificus cmcp6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQO OCA].
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*[[Ornithine carbamoyltransferase|Ornithine carbamoyltransferase]]
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__TOC__
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</StructureSection>
[[Category: Ornithine carbamoyltransferase]]
[[Category: Ornithine carbamoyltransferase]]
[[Category: Vibrio vulnificus cmcp6]]
[[Category: Vibrio vulnificus cmcp6]]
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[[Category: Anderson, W F.]]
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[[Category: Anderson, W F]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Structural genomic]]
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[[Category: Domagalski, M J.]]
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[[Category: Domagalski, M J]]
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[[Category: Grimshaw, S.]]
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[[Category: Grimshaw, S]]
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[[Category: Minor, W.]]
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[[Category: Minor, W]]
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[[Category: Shabalin, I G.]]
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[[Category: Shabalin, I G]]
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[[Category: Winsor, J.]]
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[[Category: Winsor, J]]
[[Category: Carbamoyl phosphate]]
[[Category: Carbamoyl phosphate]]
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[[Category: Center for structural genomics of infectious disease]]
 
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: L-ornithine]]
[[Category: L-ornithine]]
[[Category: National institute of allergy and infectious disease]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Niaid]]
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[[Category: Structural genomic]]
 
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 19:04, 24 December 2014

Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with citrulline and inorganic phosphate

4jqo, resolution 2.08Å

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