1z47
From Proteopedia
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| - | [[Image:1z47.gif|left|200px]] | + | [[Image:1z47.gif|left|200px]] |
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| - | '''Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius''' | + | {{Structure |
| + | |PDB= 1z47 |SIZE=350|CAPTION= <scene name='initialview01'>1z47</scene>, resolution 1.90Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=CL:CHLORIDE ION'>CL</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= cysA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=405212 Alicyclobacillus acidocaldarius]) | ||
| + | }} | ||
| + | |||
| + | '''Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1Z47 is a [ | + | 1Z47 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Alicyclobacillus_acidocaldarius Alicyclobacillus acidocaldarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z47 OCA]. |
==Reference== | ==Reference== | ||
| - | Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius., Scheffel F, Demmer U, Warkentin E, Hulsmann A, Schneider E, Ermler U, FEBS Lett. 2005 May 23;579(13):2953-8. Epub 2005 Apr 25. PMID:[http:// | + | Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius., Scheffel F, Demmer U, Warkentin E, Hulsmann A, Schneider E, Ermler U, FEBS Lett. 2005 May 23;579(13):2953-8. Epub 2005 Apr 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15893314 15893314] |
[[Category: Alicyclobacillus acidocaldarius]] | [[Category: Alicyclobacillus acidocaldarius]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: alpha/beta motif; beta sandwich]] | [[Category: alpha/beta motif; beta sandwich]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:31:01 2008'' |
Revision as of 13:31, 20 March 2008
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| , resolution 1.90Å | |||||||
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| Ligands: | |||||||
| Gene: | cysA (Alicyclobacillus acidocaldarius) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius
Overview
CysA, the ATPase subunit of a putative sulfate ATP-binding cassette transport system of the gram-positive thermoacidophilic bacterium Alicyclobacillus acidocaldarius, was structurally characterized at a resolution of 2.0 Angstroms in the absence of nucleotides. In line with previous findings on ABC-ATPases the structures of the two monomers (called CysA-1 and CysA-2) in the asymmetric unit differ substantially in the arrangement of their individual (sub)domains. CysA-2 was found as a physiological dimer composed of two crystallographically related monomers that are arranged in an open state. Interestingly, while the regulatory domain of CysA-2 packs against its opposing domain that of CysA-1 undergoes a conformational change and, in the dimer, would interfere with the opposing monomer thereby preventing solute translocation. Whether this conformational state is used for regulatory purposes will be discussed.
About this Structure
1Z47 is a Single protein structure of sequence from Alicyclobacillus acidocaldarius. Full crystallographic information is available from OCA.
Reference
Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius., Scheffel F, Demmer U, Warkentin E, Hulsmann A, Schneider E, Ermler U, FEBS Lett. 2005 May 23;579(13):2953-8. Epub 2005 Apr 25. PMID:15893314
Page seeded by OCA on Thu Mar 20 15:31:01 2008
