1ii8
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ii8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1II8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1II8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1ii8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1II8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1II8 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ii7|1ii7]], [[1f2t|1f2t]], [[1f2u|1f2u]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ii7|1ii7]], [[1f2t|1f2t]], [[1f2u|1f2u]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ii8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ii8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ii8 RCSB], [http://www.ebi.ac.uk/pdbsum/1ii8 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ii8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ii8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ii8 RCSB], [http://www.ebi.ac.uk/pdbsum/1ii8 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RAD50_PYRFU RAD50_PYRFU]] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Pyrococcus furiosus]] | [[Category: Pyrococcus furiosus]] | ||
| - | [[Category: Carney, J P | + | [[Category: Carney, J P]] |
| - | [[Category: Craig, L | + | [[Category: Craig, L]] |
| - | [[Category: Hopfner, K P | + | [[Category: Hopfner, K P]] |
| - | [[Category: Karcher, A | + | [[Category: Karcher, A]] |
| - | [[Category: Tainer, J A | + | [[Category: Tainer, J A]] |
| - | [[Category: Woo, T T | + | [[Category: Woo, T T]] |
[[Category: Dna double-strand break repair]] | [[Category: Dna double-strand break repair]] | ||
[[Category: Mre11]] | [[Category: Mre11]] | ||
[[Category: Rad50]] | [[Category: Rad50]] | ||
[[Category: Replication]] | [[Category: Replication]] | ||
Revision as of 19:30, 24 December 2014
Crystal structure of the P. furiosus Rad50 ATPase domain
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