3mpx
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mpx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mpx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mpx RCSB], [http://www.ebi.ac.uk/pdbsum/3mpx PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mpx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mpx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mpx RCSB], [http://www.ebi.ac.uk/pdbsum/3mpx PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FGD5_HUMAN FGD5_HUMAN]] Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 19:41, 24 December 2014
Crystal structure of the DH and PH-1 domains of human FGD5
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Categories: Homo sapiens | Arrowsmith, C H | Bochkarev, A | Bountra, C | Crombet, L | Edwards, A M | Nedyalkova, L | Park, H | Structural genomic | Shen, Y | Tempel, W | Tong, Y | Weigelt, J | Dh domain | Lipid binding protein | Ph domain | Sgc
