4dvh
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4dvh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycc Trycc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DVH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DVH FirstGlance]. <br> | <table><tr><td colspan='2'>[[4dvh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycc Trycc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DVH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DVH FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tc00.1047053509775.40 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tc00.1047053509775.40 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dvh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dvh RCSB], [http://www.ebi.ac.uk/pdbsum/4dvh PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dvh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dvh RCSB], [http://www.ebi.ac.uk/pdbsum/4dvh PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q4DCQ3_TRYCC Q4DCQ3_TRYCC]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).[RuleBase:RU000414] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 14: | Line 16: | ||
Structural and molecular basis of the peroxynitrite-mediated nitration and inactivation of Trypanosoma cruzi Fe-superoxide dismutases A and B: Disparate susceptibilities due to the repair of Tyr35 radical by Cys83 in Fe-SODB through intramolecular electron transfer.,Martinez A, Peluffo G, Petruk AA, Hugo M, Pineyro D, Demicheli V, Moreno D, Lima A, Batthyany C, Duran R, Robello C, Marti MA, Larrieux N, Buschiazzo A, Trujillo M, Radi R, Piacenza L J Biol Chem. 2014 Mar 10. PMID:24616096<ref>PMID:24616096</ref> | Structural and molecular basis of the peroxynitrite-mediated nitration and inactivation of Trypanosoma cruzi Fe-superoxide dismutases A and B: Disparate susceptibilities due to the repair of Tyr35 radical by Cys83 in Fe-SODB through intramolecular electron transfer.,Martinez A, Peluffo G, Petruk AA, Hugo M, Pineyro D, Demicheli V, Moreno D, Lima A, Batthyany C, Duran R, Robello C, Marti MA, Larrieux N, Buschiazzo A, Trujillo M, Radi R, Piacenza L J Biol Chem. 2014 Mar 10. PMID:24616096<ref>PMID:24616096</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Superoxide Dismutase|Superoxide Dismutase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 22: | Line 27: | ||
[[Category: Superoxide dismutase]] | [[Category: Superoxide dismutase]] | ||
[[Category: Trycc]] | [[Category: Trycc]] | ||
| - | [[Category: Buschiazzo, A | + | [[Category: Buschiazzo, A]] |
| - | [[Category: Larrieux, N | + | [[Category: Larrieux, N]] |
[[Category: Iron superoxide dismutase]] | [[Category: Iron superoxide dismutase]] | ||
[[Category: Mitochondrial]] | [[Category: Mitochondrial]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 19:42, 24 December 2014
Crystal structure of Trypanosoma cruzi mitochondrial iron superoxide dismutase
| |||||||||||
