2fq3

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2fq3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FQ3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2fq3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FQ3 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SWI3, TYE2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SWI3, TYE2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fq3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fq3 RCSB], [http://www.ebi.ac.uk/pdbsum/2fq3 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fq3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fq3 RCSB], [http://www.ebi.ac.uk/pdbsum/2fq3 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SWI3_YEAST SWI3_YEAST]] Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Cairns, B R.]]
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[[Category: Cairns, B R]]
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[[Category: Da, G.]]
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[[Category: Da, G]]
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[[Category: Lenkart, J.]]
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[[Category: Lenkart, J]]
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[[Category: Marmorstein, R.]]
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[[Category: Marmorstein, R]]
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[[Category: Shiekhattar, R.]]
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[[Category: Shiekhattar, R]]
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[[Category: Zhao, K.]]
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[[Category: Zhao, K]]
[[Category: Four-helix bundle]]
[[Category: Four-helix bundle]]
[[Category: Transcription]]
[[Category: Transcription]]

Revision as of 19:44, 24 December 2014

Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes

2fq3, resolution 1.40Å

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