1zag

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[[Image:1zag.gif|left|200px]]<br /><applet load="1zag" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1zag.gif|left|200px]]
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caption="1zag, resolution 2.80&Aring;" />
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'''HUMAN ZINC-ALPHA-2-GLYCOPROTEIN'''<br />
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{{Structure
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|PDB= 1zag |SIZE=350|CAPTION= <scene name='initialview01'>1zag</scene>, resolution 2.80&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> and <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''HUMAN ZINC-ALPHA-2-GLYCOPROTEIN'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1ZAG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene> and <scene name='pdbligand=NDG:'>NDG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZAG OCA].
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1ZAG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZAG OCA].
==Reference==
==Reference==
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Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules., Sanchez LM, Chirino AJ, Bjorkman P, Science. 1999 Mar 19;283(5409):1914-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10206894 10206894]
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Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules., Sanchez LM, Chirino AJ, Bjorkman P, Science. 1999 Mar 19;283(5409):1914-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10206894 10206894]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: secreted mhc class i homolog]]
[[Category: secreted mhc class i homolog]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:13:44 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:33:08 2008''

Revision as of 13:33, 20 March 2008

Image:1zag.gif


PDB ID 1zag

Drag the structure with the mouse to rotate
, resolution 2.80Å
Ligands: and
Coordinates: save as pdb, mmCIF, xml



HUMAN ZINC-ALPHA-2-GLYCOPROTEIN


Overview

Zn-alpha2-glycoprotein (ZAG) is a soluble protein that is present in serum and other body fluids. ZAG stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. The 2.8 angstrom crystal structure of ZAG resembles a class I major histocompatibility complex (MHC) heavy chain, but ZAG does not bind the class I light chain beta2-microglobulin. The ZAG structure includes a large groove analogous to class I MHC peptide binding grooves. Instead of a peptide, the ZAG groove contains a nonpeptidic compound that may be implicated in lipid catabolism under normal or pathological conditions.

About this Structure

1ZAG is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules., Sanchez LM, Chirino AJ, Bjorkman P, Science. 1999 Mar 19;283(5409):1914-9. PMID:10206894

Page seeded by OCA on Thu Mar 20 15:33:08 2008

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