4p6i

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4p6i]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P6I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P6I FirstGlance]. <br>
<table><tr><td colspan='2'>[[4p6i]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P6I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P6I FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p6i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p6i RCSB], [http://www.ebi.ac.uk/pdbsum/4p6i PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p6i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p6i RCSB], [http://www.ebi.ac.uk/pdbsum/4p6i PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CAS2_ECOLI CAS2_ECOLI]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity).<ref>PMID:21255106</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==See Also==
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*[[Endonuclease|Endonuclease]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Doudna, J A.]]
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[[Category: Doudna, J A]]
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[[Category: Kranzusch, P J.]]
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[[Category: Kranzusch, P J]]
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[[Category: Noeske, J.]]
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[[Category: Noeske, J]]
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[[Category: Nunez, J K.]]
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[[Category: Nunez, J K]]
[[Category: Crispr-associated protein]]
[[Category: Crispr-associated protein]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Nuclease]]
[[Category: Nuclease]]

Revision as of 19:49, 24 December 2014

Crystal structure of the Cas1-Cas2 complex from Escherichia coli

4p6i, resolution 2.30Å

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