4bew

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{{STRUCTURE_4bew| PDB=4bew | SCENE= }}
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==SERCA bound to phosphate analogue==
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===SERCA bound to phosphate analogue===
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<StructureSection load='4bew' size='340' side='right' caption='[[4bew]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4bew]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BEW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BEW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CZA:(6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1,2 2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE'>CZA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MGF:TRIFLUOROMAGNESATE'>MGF</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bew OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bew RCSB], [http://www.ebi.ac.uk/pdbsum/4bew PDBsum]</span></td></tr>
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</table>
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== Function ==
[[http://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT]] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
[[http://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT]] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4bew]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BEW OCA].
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[[Category: Calcium-transporting ATPase]]
[[Category: Calcium-transporting ATPase]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: Bublitz, M.]]
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[[Category: Bublitz, M]]
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[[Category: Drachmann, N D.]]
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[[Category: Drachmann, N D]]
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[[Category: Laursen, M.]]
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[[Category: Laursen, M]]
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[[Category: Mattle, D.]]
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[[Category: Mattle, D]]
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[[Category: Moeller, J V.]]
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[[Category: Moeller, J V]]
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[[Category: Morth, J P.]]
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[[Category: Morth, J P]]
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[[Category: Nissen, P.]]
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[[Category: Nissen, P]]
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[[Category: Olesen, C.]]
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[[Category: Olesen, C]]
[[Category: Calcium transport]]
[[Category: Calcium transport]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Ion transport]]
[[Category: Ion transport]]
[[Category: P-type atpase]]
[[Category: P-type atpase]]

Revision as of 19:56, 24 December 2014

SERCA bound to phosphate analogue

4bew, resolution 2.50Å

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