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4bew
From Proteopedia
(Difference between revisions)
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| - | + | ==SERCA bound to phosphate analogue== | |
| - | === | + | <StructureSection load='4bew' size='340' side='right' caption='[[4bew]], [[Resolution|resolution]] 2.50Å' scene=''> |
| - | + | == Structural highlights == | |
| - | ==Function== | + | <table><tr><td colspan='2'>[[4bew]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BEW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BEW FirstGlance]. <br> |
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CZA:(6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1,2 2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE'>CZA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MGF:TRIFLUOROMAGNESATE'>MGF</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bew OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bew RCSB], [http://www.ebi.ac.uk/pdbsum/4bew PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT]] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity). | [[http://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT]] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity). | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Calcium-transporting ATPase]] | [[Category: Calcium-transporting ATPase]] | ||
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
| - | [[Category: Bublitz, M | + | [[Category: Bublitz, M]] |
| - | [[Category: Drachmann, N D | + | [[Category: Drachmann, N D]] |
| - | [[Category: Laursen, M | + | [[Category: Laursen, M]] |
| - | [[Category: Mattle, D | + | [[Category: Mattle, D]] |
| - | [[Category: Moeller, J V | + | [[Category: Moeller, J V]] |
| - | [[Category: Morth, J P | + | [[Category: Morth, J P]] |
| - | [[Category: Nissen, P | + | [[Category: Nissen, P]] |
| - | [[Category: Olesen, C | + | [[Category: Olesen, C]] |
[[Category: Calcium transport]] | [[Category: Calcium transport]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Ion transport]] | [[Category: Ion transport]] | ||
[[Category: P-type atpase]] | [[Category: P-type atpase]] | ||
Revision as of 19:56, 24 December 2014
SERCA bound to phosphate analogue
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