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3qci

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3qci]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QCI FirstGlance]. <br>
<table><tr><td colspan='2'>[[3qci]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QCI FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NX3:N-[(3-AMINOPHENYL)SULFONYL]-3-[(3,4-DICHLOROBENZYL)SULFANYL]THIOPHENE-2-CARBOXAMIDE'>NX3</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NX3:N-[(3-AMINOPHENYL)SULFONYL]-3-[(3,4-DICHLOROBENZYL)SULFANYL]THIOPHENE-2-CARBOXAMIDE'>NX3</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qcb|3qcb]], [[3qcc|3qcc]], [[3qcd|3qcd]], [[3qce|3qce]], [[3qcf|3qcf]], [[3qcg|3qcg]], [[3qch|3qch]], [[3qcj|3qcj]], [[3qck|3qck]], [[3qcl|3qcl]], [[3qcm|3qcm]], [[3qcn|3qcn]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qcb|3qcb]], [[3qcc|3qcc]], [[3qcd|3qcd]], [[3qce|3qce]], [[3qcf|3qcf]], [[3qcg|3qcg]], [[3qch|3qch]], [[3qcj|3qcj]], [[3qck|3qck]], [[3qcl|3qcl]], [[3qcm|3qcm]], [[3qcn|3qcn]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPG, PTPRG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPG, PTPRG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qci OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qci RCSB], [http://www.ebi.ac.uk/pdbsum/3qci PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qci OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qci RCSB], [http://www.ebi.ac.uk/pdbsum/3qci PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PTPRG_HUMAN PTPRG_HUMAN]] Possesses tyrosine phosphatase activity.<ref>PMID:19167335</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Sheriff, S.]]
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[[Category: Sheriff, S]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Twisted mixed beta-sheets flanked by {alpha}-helice]]
[[Category: Twisted mixed beta-sheets flanked by {alpha}-helice]]
[[Category: Tyrosine receptor phosphatase]]
[[Category: Tyrosine receptor phosphatase]]

Revision as of 20:05, 24 December 2014

Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with N-[(3-aminophenyl)sulfonyl]-3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxamide

3qci, resolution 2.27Å

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[[Category: Twisted mixed beta-sheets flanked by {alpha}-helice]]

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