1zfq
From Proteopedia
(Difference between revisions)
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- | [[Image:1zfq.gif|left|200px]] | + | [[Image:1zfq.gif|left|200px]] |
- | + | ||
- | '''carbonic anhydrase II in complex with ethoxzolamidphenole as sulfonamide inhibitor''' | + | {{Structure |
+ | |PDB= 1zfq |SIZE=350|CAPTION= <scene name='initialview01'>1zfq</scene>, resolution 1.55Å | ||
+ | |SITE= | ||
+ | |LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=ZEC:6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE'>ZEC</scene>, <scene name='pdbligand=BE7:(4-CARBOXYPHENYL)(CHLORO)MERCURY'>BE7</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | ||
+ | |ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] | ||
+ | |GENE= CA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
+ | }} | ||
+ | |||
+ | '''carbonic anhydrase II in complex with ethoxzolamidphenole as sulfonamide inhibitor''' | ||
+ | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
- | 1ZFQ is a [ | + | 1ZFQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZFQ OCA]. |
[[Category: Carbonate dehydratase]] | [[Category: Carbonate dehydratase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: ZN]] | [[Category: ZN]] | ||
[[Category: 10 stranded]] | [[Category: 10 stranded]] | ||
- | [[Category: twisted beta- | + | [[Category: twisted beta-sheet]] |
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:34:55 2008'' |
Revision as of 13:34, 20 March 2008
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, resolution 1.55Å | |||||||
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Ligands: | , , and | ||||||
Gene: | CA2 (Homo sapiens) | ||||||
Activity: | Carbonate dehydratase, with EC number 4.2.1.1 | ||||||
Coordinates: | save as pdb, mmCIF, xml |
carbonic anhydrase II in complex with ethoxzolamidphenole as sulfonamide inhibitor
Disease
Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]
About this Structure
1ZFQ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 15:34:55 2008
Categories: Carbonate dehydratase | Homo sapiens | Single protein | Heine, A. | Honndorf, V S. | Klebe, G. | Supuran, C T. | BE7 | GOL | ZEC | ZN | 10 stranded | Twisted beta-sheet