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4ea4
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ea4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ea4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ea4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ea4 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ea4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ea4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ea4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ea4 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MBD4_HUMAN MBD4_HUMAN]] Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.<ref>PMID:10097147</ref> <ref>PMID:10930409</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 20:11, 24 December 2014
Structure of the glycosylase domain of MBD4 bound to 5hmU-containing DNA
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