2m0y
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m0y RCSB], [http://www.ebi.ac.uk/pdbsum/2m0y PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m0y RCSB], [http://www.ebi.ac.uk/pdbsum/2m0y PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DOCK1_MOUSE DOCK1_MOUSE]] Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 20:32, 24 December 2014
Solution structure of the SH3 domain of DOCK180
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Categories: Mus musculus | Liu, X | Wen, W | Apoptosis
