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4bj3
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bj3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bj3 RCSB], [http://www.ebi.ac.uk/pdbsum/4bj3 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bj3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bj3 RCSB], [http://www.ebi.ac.uk/pdbsum/4bj3 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ITA2_HUMAN ITA2_HUMAN]] Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 20:34, 24 December 2014
Integrin alpha2 I domain E318W-collagen complex
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