2mah
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2mah]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MAH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MAH FirstGlance]. <br> | <table><tr><td colspan='2'>[[2mah]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MAH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MAH FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">smo, CG11561 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">smo, CG11561 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mah OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mah RCSB], [http://www.ebi.ac.uk/pdbsum/2mah PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mah OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mah RCSB], [http://www.ebi.ac.uk/pdbsum/2mah PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SMO_DROME SMO_DROME]] Segment polarity protein required for correct patterning of every segment. G protein-coupled receptor that associates with the patched protein (ptc) to transduce the hedgehog (hh) signal through the activation of an inhibitory G-protein. In the absence of hh, ptc represses the constitutive signaling activity of smo through fused (fu). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling.,Rana R, Carroll CE, Lee HJ, Bao J, Marada S, Grace CR, Guibao CD, Ogden SK, Zheng JJ Nat Commun. 2013;4:2965. doi: 10.1038/ncomms3965. PMID:24351982<ref>PMID:24351982</ref> | Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling.,Rana R, Carroll CE, Lee HJ, Bao J, Marada S, Grace CR, Guibao CD, Ogden SK, Zheng JJ Nat Commun. 2013;4:2965. doi: 10.1038/ncomms3965. PMID:24351982<ref>PMID:24351982</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Drome]] | [[Category: Drome]] | ||
| - | [[Category: Lee, H | + | [[Category: Lee, H]] |
| - | [[Category: Rana, R | + | [[Category: Rana, R]] |
| - | [[Category: Zheng, J J | + | [[Category: Zheng, J J]] |
[[Category: Hedgehog]] | [[Category: Hedgehog]] | ||
[[Category: Oncoprotein]] | [[Category: Oncoprotein]] | ||
[[Category: Smoothened]] | [[Category: Smoothened]] | ||
Revision as of 20:47, 24 December 2014
Solution structure of Smoothened
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Categories: Drome | Lee, H | Rana, R | Zheng, J J | Hedgehog | Oncoprotein | Smoothened
