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1zpa

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[[Image:1zpa.gif|left|200px]]<br /><applet load="1zpa" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1zpa.gif|left|200px]]
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caption="1zpa, resolution 2.02&Aring;" />
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'''HIV Protease with Scripps AB-3 Inhibitor'''<br />
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{{Structure
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|PDB= 1zpa |SIZE=350|CAPTION= <scene name='initialview01'>1zpa</scene>, resolution 2.02&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=A83:TERT-BUTYL 4-[({[1-((1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL}AMINO)CARBONYL]BENZYLCARBAMATE'>A83</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16]
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|GENE=
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}}
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'''HIV Protease with Scripps AB-3 Inhibitor'''
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==About this Structure==
==About this Structure==
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1ZPA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=A83:'>A83</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPA OCA].
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1ZPA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPA OCA].
==Reference==
==Reference==
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1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors., Brik A, Alexandratos J, Lin YC, Elder JH, Olson AJ, Wlodawer A, Goodsell DS, Wong CH, Chembiochem. 2005 Jul;6(7):1167-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15934050 15934050]
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1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors., Brik A, Alexandratos J, Lin YC, Elder JH, Olson AJ, Wlodawer A, Goodsell DS, Wong CH, Chembiochem. 2005 Jul;6(7):1167-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15934050 15934050]
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: retroviral]]
[[Category: retroviral]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:17:51 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:38:17 2008''

Revision as of 13:38, 20 March 2008

Image:1zpa.gif


PDB ID 1zpa

Drag the structure with the mouse to rotate
, resolution 2.02Å
Ligands:
Activity: HIV-1 retropepsin, with EC number 3.4.23.16
Coordinates: save as pdb, mmCIF, xml



HIV Protease with Scripps AB-3 Inhibitor


About this Structure

1ZPA is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors., Brik A, Alexandratos J, Lin YC, Elder JH, Olson AJ, Wlodawer A, Goodsell DS, Wong CH, Chembiochem. 2005 Jul;6(7):1167-9. PMID:15934050

Page seeded by OCA on Thu Mar 20 15:38:17 2008

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