1s31
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1s31]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S31 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1S31 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1s31]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S31 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1S31 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1c8z|1c8z]], [[1i7e|1i7e]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1c8z|1c8z]], [[1i7e|1i7e]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tub ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tub ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s31 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1s31 RCSB], [http://www.ebi.ac.uk/pdbsum/1s31 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s31 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1s31 RCSB], [http://www.ebi.ac.uk/pdbsum/1s31 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TUB_HUMAN TUB_HUMAN]] Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight (By similarity). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Abitbol, M | + | [[Category: Abitbol, M]] |
| - | [[Category: Basdevant, A | + | [[Category: Basdevant, A]] |
| - | [[Category: Boutboul, S | + | [[Category: Boutboul, S]] |
| - | [[Category: Carroll, K J | + | [[Category: Carroll, K J]] |
| - | [[Category: Clement, K | + | [[Category: Clement, K]] |
| - | [[Category: Gomez, C | + | [[Category: Gomez, C]] |
| - | [[Category: Nandrot, E | + | [[Category: Nandrot, E]] |
| - | [[Category: Shapiro, L | + | [[Category: Shapiro, L]] |
[[Category: Beta barrel]] | [[Category: Beta barrel]] | ||
[[Category: Hydrophobic core]] | [[Category: Hydrophobic core]] | ||
[[Category: Hydrophobic helix]] | [[Category: Hydrophobic helix]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
Revision as of 21:04, 24 December 2014
Crystal Structure Analysis of the human Tub protein (isoform a) spanning residues 289 through 561
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