1hsm
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1hsm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HSM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HSM FirstGlance]. <br> | <table><tr><td colspan='2'>[[1hsm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HSM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HSM FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hsn|1hsn]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hsn|1hsn]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">INSERT DERIVED BY PCR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10029 Cricetulus griseus])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">INSERT DERIVED BY PCR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10029 Cricetulus griseus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hsm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hsm RCSB], [http://www.ebi.ac.uk/pdbsum/1hsm PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hsm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hsm RCSB], [http://www.ebi.ac.uk/pdbsum/1hsm PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HMGB1_CRIGR HMGB1_CRIGR]] DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Cricetulus griseus]] | [[Category: Cricetulus griseus]] | ||
| - | [[Category: Carillo, M O.M | + | [[Category: Carillo, M O.M]] |
| - | [[Category: Cary, P D | + | [[Category: Cary, P D]] |
| - | [[Category: Crane-Robinson, C | + | [[Category: Crane-Robinson, C]] |
| - | [[Category: Driscoll, P C | + | [[Category: Driscoll, P C]] |
| - | [[Category: Norman, D G | + | [[Category: Norman, D G]] |
| - | [[Category: Read, C M | + | [[Category: Read, C M]] |
[[Category: Dna-binding]] | [[Category: Dna-binding]] | ||
Revision as of 21:18, 24 December 2014
THE STRUCTURE OF THE HMG BOX AND ITS INTERACTION WITH DNA
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