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1qax

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1qax]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QAX FirstGlance]. <br>
<table><tr><td colspan='2'>[[1qax]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QAX FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HMG:3-HYDROXY-3-METHYLGLUTARYL-COENZYME+A'>HMG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HMG:3-HYDROXY-3-METHYLGLUTARYL-COENZYME+A'>HMG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MVAA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32044 Pseudomonas mevalonii])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MVAA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32044 Pseudomonas mevalonii])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qax OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qax RCSB], [http://www.ebi.ac.uk/pdbsum/1qax PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qax OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qax RCSB], [http://www.ebi.ac.uk/pdbsum/1qax PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV]] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Pseudomonas mevalonii]]
[[Category: Pseudomonas mevalonii]]
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[[Category: Bochar, D A.]]
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[[Category: Bochar, D A]]
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[[Category: Rodwell, V W.]]
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[[Category: Rodwell, V W]]
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[[Category: Stauffacher, C V.]]
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[[Category: Stauffacher, C V]]
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[[Category: Tabernero, L.]]
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[[Category: Tabernero, L]]
[[Category: 4-electron oxido-reductase]]
[[Category: 4-electron oxido-reductase]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 21:18, 24 December 2014

TERNARY COMPLEX OF PSEUDOMONAS MEVALONII HMG-COA REDUCTASE WITH HMG-COA AND NAD+

1qax, resolution 2.80Å

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