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1zys

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[[Image:1zys.gif|left|200px]]<br /><applet load="1zys" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1zys.gif|left|200px]]
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caption="1zys, resolution 1.70&Aring;" />
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'''Co-crystal structure of Checkpoint Kinase Chk1 with a pyrrolo-pyridine inhibitor'''<br />
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{{Structure
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|PDB= 1zys |SIZE=350|CAPTION= <scene name='initialview01'>1zys</scene>, resolution 1.70&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=199:N-{5-[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL}NICOTINAMIDE'>199</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
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|GENE= CHEK1, CHK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Co-crystal structure of Checkpoint Kinase Chk1 with a pyrrolo-pyridine inhibitor'''
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==About this Structure==
==About this Structure==
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1ZYS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=199:'>199</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYS OCA].
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1ZYS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYS OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: chk1; crystal structure]]
[[Category: chk1; crystal structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:20:29 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:41:25 2008''

Revision as of 13:41, 20 March 2008

Image:1zys.gif


PDB ID 1zys

Drag the structure with the mouse to rotate
, resolution 1.70Å
Ligands: and
Gene: CHEK1, CHK1 (Homo sapiens)
Activity: Non-specific serine/threonine protein kinase, with EC number 2.7.11.1
Coordinates: save as pdb, mmCIF, xml



Co-crystal structure of Checkpoint Kinase Chk1 with a pyrrolo-pyridine inhibitor


About this Structure

1ZYS is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 15:41:25 2008

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