2yjy
From Proteopedia
(Difference between revisions)
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<StructureSection load='2yjy' size='340' side='right' caption='[[2yjy]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='2yjy' size='340' side='right' caption='[[2yjy]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2yjy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YJY OCA]. <br> | + | <table><tr><td colspan='2'>[[2yjy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YJY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YJY FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ib2|1ib2]], [[1m8y|1m8y]], [[1m8z|1m8z]], [[1m8w|1m8w]], [[1m8x|1m8x]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ib2|1ib2]], [[1m8y|1m8y]], [[1m8z|1m8z]], [[1m8w|1m8w]], [[1m8x|1m8x]]</td></tr> |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yjy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yjy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yjy RCSB], [http://www.ebi.ac.uk/pdbsum/2yjy PDBsum]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/PUM1_HUMAN PUM1_HUMAN]] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Specific and Modular Binding Code for Cytosine Recognition in Pumilio/FBF (PUF) RNA-binding Domains.,Dong S, Wang Y, Cassidy-Amstutz C, Lu G, Bigler R, Jezyk MR, Li C, Hall TM, Wang Z J Biol Chem. 2011 Jul 29;286(30):26732-42. Epub 2011 Jun 8. PMID:21653694<ref>PMID:21653694</ref> | Specific and Modular Binding Code for Cytosine Recognition in Pumilio/FBF (PUF) RNA-binding Domains.,Dong S, Wang Y, Cassidy-Amstutz C, Lu G, Bigler R, Jezyk MR, Li C, Hall TM, Wang Z J Biol Chem. 2011 Jul 29;286(30):26732-42. Epub 2011 Jun 8. PMID:21653694<ref>PMID:21653694</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Bigler, R | + | [[Category: Bigler, R]] |
| - | [[Category: Cassidy-Amstutz, C | + | [[Category: Cassidy-Amstutz, C]] |
| - | [[Category: Dong, S | + | [[Category: Dong, S]] |
| - | [[Category: Hall, T M.T | + | [[Category: Hall, T M.T]] |
| - | [[Category: Jezyk, M | + | [[Category: Jezyk, M]] |
| - | [[Category: Li, C | + | [[Category: Li, C]] |
| - | [[Category: Lu, G | + | [[Category: Lu, G]] |
| - | [[Category: Qiu, C | + | [[Category: Qiu, C]] |
| - | [[Category: Wang, Y | + | [[Category: Wang, Y]] |
| - | [[Category: Wang, Z | + | [[Category: Wang, Z]] |
[[Category: Nanos response element]] | [[Category: Nanos response element]] | ||
[[Category: Rna binding protein-rna complex]] | [[Category: Rna binding protein-rna complex]] | ||
Revision as of 21:45, 24 December 2014
A SPECIFIC AND MODULAR BINDING CODE FOR CYTOSINE RECOGNITION IN PUF DOMAINS
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