1np4
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1np4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NP4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NP4 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1np4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NP4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NP4 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NH3:AMMONIA'>NH3</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NH3:AMMONIA'>NH3</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1np4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1np4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1np4 RCSB], [http://www.ebi.ac.uk/pdbsum/1np4 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1np4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1np4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1np4 RCSB], [http://www.ebi.ac.uk/pdbsum/1np4 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR]] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Rhodnius prolixus]] | [[Category: Rhodnius prolixus]] | ||
| - | [[Category: Andersen, J F | + | [[Category: Andersen, J F]] |
| - | [[Category: Balfour, C A | + | [[Category: Balfour, C A]] |
| - | [[Category: Champagne, D E | + | [[Category: Champagne, D E]] |
| - | [[Category: Montfort, W R | + | [[Category: Montfort, W R]] |
| - | [[Category: Weichsel, A | + | [[Category: Weichsel, A]] |
[[Category: Antihistamine]] | [[Category: Antihistamine]] | ||
[[Category: Bilin binding protein]] | [[Category: Bilin binding protein]] | ||
Revision as of 21:47, 24 December 2014
CRYSTAL STRUCTURE OF NITROPHORIN 4 FROM RHODNIUS PROLIXUS
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