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3t9k
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t9k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t9k RCSB], [http://www.ebi.ac.uk/pdbsum/3t9k PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t9k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t9k RCSB], [http://www.ebi.ac.uk/pdbsum/3t9k PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ACAP1_HUMAN ACAP1_HUMAN]] GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.<ref>PMID:11062263</ref> <ref>PMID:16256741</ref> <ref>PMID:17398097</ref> <ref>PMID:17664335</ref> <ref>PMID:22645133</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 21:55, 24 December 2014
Crystal Structure of ACAP1 C-portion mutant S554D fused with integrin beta1 peptide
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