216d
From Proteopedia
(Difference between revisions)
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| - | [[Image:216d.jpg|left|200px]] | + | [[Image:216d.jpg|left|200px]] |
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| - | '''CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN''' | + | {{Structure |
| + | |PDB= 216d |SIZE=350|CAPTION= <scene name='initialview01'>216d</scene>, resolution 1.730Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=DMY:DISTAMYCIN+A'>DMY</scene> and <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 216D is a [ | + | 216D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=216D OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:[http:// | + | Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7552741 7552741] |
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Chen, X.]] | [[Category: Chen, X.]] | ||
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[[Category: modified]] | [[Category: modified]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:42:12 2008'' |
Revision as of 13:42, 20 March 2008
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| , resolution 1.730Å | |||||||
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| Ligands: | and | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN
Overview
Two DNA-RNA chimers, complexed with DNA minor groove binding drugs, have been observed to adopt the B-form conformation for the first time. Thus, the RNA duplex may assume the B-DNA conformation when interacting with drugs, peptides or proteins.
About this Structure
216D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:7552741
Page seeded by OCA on Thu Mar 20 15:42:12 2008
