1pjr

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1pjr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PJR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PJR FirstGlance]. <br>
<table><tr><td colspan='2'>[[1pjr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PJR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PJR FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PCRA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 Geobacillus stearothermophilus])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PCRA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 Geobacillus stearothermophilus])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pjr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pjr RCSB], [http://www.ebi.ac.uk/pdbsum/1pjr PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pjr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pjr RCSB], [http://www.ebi.ac.uk/pdbsum/1pjr PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PCRA_BACST PCRA_BACST]] DNA helicase. Has a broad nucleotide specificity, even being able to hydrolyze ethenonucleotides, and is able to couple the hydrolysis to unwinding of DNA substrates. It is a 3'-5' helicase but at high protein concentrations it can also displace a substrate with a 5' tail. Preferred substrate being one with both single and double-stranded regions of DNA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
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[[Category: Bird, L E.]]
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[[Category: Bird, L E]]
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[[Category: Brannigan, J A.]]
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[[Category: Brannigan, J A]]
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[[Category: Subramanya, H S.]]
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[[Category: Subramanya, H S]]
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[[Category: Wigley, D B.]]
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[[Category: Wigley, D B]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Dna repair]]
[[Category: Dna repair]]

Revision as of 22:22, 24 December 2014

STRUCTURE OF DNA HELICASE

1pjr, resolution 2.50Å

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