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1x37
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1x37]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X37 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1X37 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1x37]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X37 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1X37 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_La Endopeptidase La], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.53 3.4.21.53] </span></td></tr> | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_La Endopeptidase La], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.53 3.4.21.53] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x37 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1x37 RCSB], [http://www.ebi.ac.uk/pdbsum/1x37 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x37 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1x37 RCSB], [http://www.ebi.ac.uk/pdbsum/1x37 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LON1_BACSU LON1_BACSU]] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity). Has been implicated in preventing sigma(G) activity under non-sporulation conditions.[HAMAP-Rule:MF_01973] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Endopeptidase La]] | [[Category: Endopeptidase La]] | ||
| - | [[Category: Chen, C | + | [[Category: Chen, C]] |
| - | [[Category: Lee, Y L | + | [[Category: Lee, Y L]] |
| - | [[Category: Lo, S C | + | [[Category: Lo, S C]] |
| - | [[Category: Lou, Y C | + | [[Category: Lou, Y C]] |
| - | [[Category: Wang, I | + | [[Category: Wang, I]] |
| - | [[Category: Wu, S H | + | [[Category: Wu, S H]] |
[[Category: Aaa+ superfamily]] | [[Category: Aaa+ superfamily]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 22:27, 24 December 2014
Structure of Bacillus subtilis Lon protease SSD domain
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Categories: Bacillus subtilis | Endopeptidase La | Chen, C | Lee, Y L | Lo, S C | Lou, Y C | Wang, I | Wu, S H | Aaa+ superfamily | Hydrolase | Protease | Solution structure | Ssd domain
