3dbo

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dbo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dbo RCSB], [http://www.ebi.ac.uk/pdbsum/3dbo PDBsum], [http://www.topsan.org/Proteins/ISFI/3dbo TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dbo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dbo RCSB], [http://www.ebi.ac.uk/pdbsum/3dbo PDBsum], [http://www.topsan.org/Proteins/ISFI/3dbo TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/P96916_MYCTU P96916_MYCTU]] Probable antitoxin component of a probable toxin-antitoxin (TA) module. The cognate toxin is VapC5 (By similarity). [[http://www.uniprot.org/uniprot/P96917_MYCTU P96917_MYCTU]] Probable toxic component of a probable toxin-antitoxin (TA) module. The cognate antitoxin is VapB5. Has limited RNase activity on substrates; activity is seen with a VapC5-VapB5 complex.<ref>PMID:18952600</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 22:28, 24 December 2014

Crystal structure of a member of the VapBC family of toxin-antitoxin systems, VapBC-5, from Mycobacterium tuberculosis

3dbo, resolution 1.76Å

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