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3f2b
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3f2b]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_kaustophilus Geobacillus kaustophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3F2B FirstGlance]. <br> | <table><tr><td colspan='2'>[[3f2b]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_kaustophilus Geobacillus kaustophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3F2B FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DGT:2-DEOXYGUANOSINE-5-TRIPHOSPHATE'>DGT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DGT:2-DEOXYGUANOSINE-5-TRIPHOSPHATE'>DGT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3f2c|3f2c]], [[3f2d|3f2d]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3f2c|3f2c]], [[3f2d|3f2d]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GK1258, polC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1462 Geobacillus kaustophilus])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GK1258, polC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1462 Geobacillus kaustophilus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3f2b RCSB], [http://www.ebi.ac.uk/pdbsum/3f2b PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3f2b RCSB], [http://www.ebi.ac.uk/pdbsum/3f2b PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q5L0J3_GEOKA Q5L0J3_GEOKA]] Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity).[HAMAP-Rule:MF_00356][SAAS:SAAS029460_004_008054] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: DNA-directed DNA polymerase]] | [[Category: DNA-directed DNA polymerase]] | ||
[[Category: Geobacillus kaustophilus]] | [[Category: Geobacillus kaustophilus]] | ||
| - | [[Category: Bullard, J M | + | [[Category: Bullard, J M]] |
| - | [[Category: Christensen, J | + | [[Category: Christensen, J]] |
| - | [[Category: Davies, D R | + | [[Category: Davies, D R]] |
| - | [[Category: Evans, R J | + | [[Category: Evans, R J]] |
| - | [[Category: Green, L S | + | [[Category: Green, L S]] |
| - | [[Category: Guiles, J W | + | [[Category: Guiles, J W]] |
| - | [[Category: Janjic, N | + | [[Category: Janjic, N]] |
| - | [[Category: Jarvis, T C | + | [[Category: Jarvis, T C]] |
| - | [[Category: Ribble, W K | + | [[Category: Ribble, W K]] |
[[Category: Dna polymerase c]] | [[Category: Dna polymerase c]] | ||
[[Category: Dna polymerase iii]] | [[Category: Dna polymerase iii]] | ||
Revision as of 22:31, 24 December 2014
DNA Polymerase PolC from Geobacillus kaustophilus complex with DNA, dGTP, Mg and Zn
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Categories: DNA-directed DNA polymerase | Geobacillus kaustophilus | Bullard, J M | Christensen, J | Davies, D R | Evans, R J | Green, L S | Guiles, J W | Janjic, N | Jarvis, T C | Ribble, W K | Dna polymerase c | Dna polymerase iii | Dna replication | Dna-directed dna polymerase | Exonuclease | Hydrolase | Nuclease | Nucleotidyltransferase | Protein-dna complex | Replicative dna polymerase | Ternary complex | Transferase | Transferase-dna complex
