This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2a1h
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:2a1h.gif|left|200px]] | + | [[Image:2a1h.gif|left|200px]] |
| - | + | ||
| - | '''X-ray crystal structure of human mitochondrial branched chain aminotransferase (BCATm) complexed with gabapentin''' | + | {{Structure |
| + | |PDB= 2a1h |SIZE=350|CAPTION= <scene name='initialview01'>2a1h</scene>, resolution 1.800Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=PLP:PYRIDOXAL-5'-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=GBN:[1-(AMINOMETHYL)CYCLOHEXYL]ACETIC+ACID'>GBN</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Branched-chain-amino-acid_transaminase Branched-chain-amino-acid transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.42 2.6.1.42] | ||
| + | |GENE= mitochondrial BCAT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | }} | ||
| + | |||
| + | '''X-ray crystal structure of human mitochondrial branched chain aminotransferase (BCATm) complexed with gabapentin''' | ||
| + | |||
==Disease== | ==Disease== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2A1H is a [ | + | 2A1H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A1H OCA]. |
[[Category: Branched-chain-amino-acid transaminase]] | [[Category: Branched-chain-amino-acid transaminase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 23: | Line 32: | ||
[[Category: fold type iv]] | [[Category: fold type iv]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:44:14 2008'' |
Revision as of 13:44, 20 March 2008
| |||||||
| , resolution 1.800Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , and | ||||||
| Gene: | mitochondrial BCAT (Homo sapiens) | ||||||
| Activity: | Branched-chain-amino-acid transaminase, with EC number 2.6.1.42 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
X-ray crystal structure of human mitochondrial branched chain aminotransferase (BCATm) complexed with gabapentin
Disease
Known diseases associated with this structure: Hypervalinemia or hyperleucine-isoleucinemia (1) OMIM:[113530]
About this Structure
2A1H is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 15:44:14 2008
