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2i7x

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2i7x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I7X FirstGlance]. <br>
<table><tr><td colspan='2'>[[2i7x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I7X FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2i7t|2i7t]], [[2i7v|2i7v]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2i7t|2i7t]], [[2i7v|2i7v]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CFT2, YDH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CFT2, YDH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i7x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2i7x RCSB], [http://www.ebi.ac.uk/pdbsum/2i7x PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i7x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2i7x RCSB], [http://www.ebi.ac.uk/pdbsum/2i7x PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CFT2_YEAST CFT2_YEAST]] RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. May be involved in poly(A)-site recognition. May be involved in the association of the CPF, CPFIA and RNA polymerase II complexes.<ref>PMID:11406596</ref> <ref>PMID:12853609</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Gebauer, D.]]
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[[Category: Gebauer, D]]
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[[Category: Mandel, C R.]]
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[[Category: Mandel, C R]]
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[[Category: Tong, L.]]
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[[Category: Tong, L]]
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[[Category: Zhang, H.]]
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[[Category: Zhang, H]]
[[Category: Artemi]]
[[Category: Artemi]]
[[Category: Double-strand break repair]]
[[Category: Double-strand break repair]]

Revision as of 22:38, 24 December 2014

Structure of Yeast CPSF-100 (Ydh1p)

2i7x, resolution 2.50Å

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