1y7n

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1y7n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y7N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Y7N FirstGlance]. <br>
<table><tr><td colspan='2'>[[1y7n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y7N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Y7N FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APBA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APBA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y7n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1y7n RCSB], [http://www.ebi.ac.uk/pdbsum/1y7n PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y7n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1y7n RCSB], [http://www.ebi.ac.uk/pdbsum/1y7n PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/APBA1_HUMAN APBA1_HUMAN]] Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Brouwer, J.]]
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[[Category: Brouwer, J]]
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[[Category: Canters, G W.]]
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[[Category: Canters, G W]]
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[[Category: Drijfhout, J W.]]
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[[Category: Drijfhout, J W]]
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[[Category: Duquesne, A E.]]
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[[Category: Duquesne, A E]]
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[[Category: Nabuurs, S B.]]
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[[Category: Nabuurs, S B]]
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[[Category: Ruijter, M de.]]
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[[Category: Ruijter, M de]]
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[[Category: Spronk, C A.E M.]]
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[[Category: Spronk, C A.E M]]
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[[Category: Ubbink, M.]]
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[[Category: Ubbink, M]]
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[[Category: Vuister, G W.]]
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[[Category: Vuister, G W]]
[[Category: Copper chaperone for superoxide dismutase]]
[[Category: Copper chaperone for superoxide dismutase]]
[[Category: Neuronal adaptor]]
[[Category: Neuronal adaptor]]
[[Category: Protein transport]]
[[Category: Protein transport]]

Revision as of 22:38, 24 December 2014

Solution structure of the second PDZ domain of the human neuronal adaptor X11alpha

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