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3ezz
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3ezz]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EZZ FirstGlance]. <br> | <table><tr><td colspan='2'>[[3ezz]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EZZ FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DUSP4, MKP2, VH2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DUSP4, MKP2, VH2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ezz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ezz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ezz RCSB], [http://www.ebi.ac.uk/pdbsum/3ezz PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ezz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ezz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ezz RCSB], [http://www.ebi.ac.uk/pdbsum/3ezz PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DUS4_HUMAN DUS4_HUMAN]] Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Jeong, D G | + | [[Category: Jeong, D G]] |
| - | [[Category: Jung, S K | + | [[Category: Jung, S K]] |
| - | [[Category: Kim, S J | + | [[Category: Kim, S J]] |
| - | [[Category: Ryu, S E | + | [[Category: Ryu, S E]] |
[[Category: Alpha/beta]] | [[Category: Alpha/beta]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Nucleus]] | [[Category: Nucleus]] | ||
[[Category: Protein phosphatase]] | [[Category: Protein phosphatase]] | ||
Revision as of 22:39, 24 December 2014
Crystal Structure of human MKP-2
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Categories: Homo sapiens | Jeong, D G | Jung, S K | Kim, S J | Ryu, S E | Alpha/beta | Hydrolase | Nucleus | Protein phosphatase
