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4ir5
From Proteopedia
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| - | + | ==Crystal Structure of the bromodomain of human BAZ2B in complex with 1-{1-[2-(hydroxymethyl)phenyl]-7-phenoxyindolizin-3-yl}ethanone (GSK2847449A)== | |
| - | + | <StructureSection load='4ir5' size='340' side='right' caption='[[4ir5]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ir5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IR5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IR5:1-{1-[2-(HYDROXYMETHYL)PHENYL]-7-PHENOXYINDOLIZIN-3-YL}ETHANONE'>IR5</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ir3|4ir3]], [[4ir4|4ir4]], [[4ir6|4ir6]]</td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAZ2B, KIAA1476 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ir5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ir5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ir5 RCSB], [http://www.ebi.ac.uk/pdbsum/4ir5 PDBsum]</span></td></tr> |
| - | [[4ir5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IR5 OCA]. | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Chaikuad, A | + | [[Category: Chaikuad, A]] |
| - | [[Category: Chen, P | + | [[Category: Chen, P]] |
| - | [[Category: Chung, C W | + | [[Category: Chung, C W]] |
| - | [[Category: Delft, F von | + | [[Category: Delft, F von]] |
| - | [[Category: Drewry, D | + | [[Category: Drewry, D]] |
| - | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
| - | [[Category: Fedorov, O | + | [[Category: Fedorov, O]] |
| - | [[Category: Felletar, I | + | [[Category: Felletar, I]] |
| - | [[Category: Filippakopoulos, P | + | [[Category: Filippakopoulos, P]] |
| - | [[Category: Knapp, S | + | [[Category: Knapp, S]] |
| - | [[Category: Krojer, T | + | [[Category: Krojer, T]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
[[Category: Acetylated lysine binding protein]] | [[Category: Acetylated lysine binding protein]] | ||
[[Category: Bromodomain]] | [[Category: Bromodomain]] | ||
[[Category: Kiaa1476]] | [[Category: Kiaa1476]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Walp4]] | [[Category: Walp4]] | ||
Revision as of 22:43, 24 December 2014
Crystal Structure of the bromodomain of human BAZ2B in complex with 1-{1-[2-(hydroxymethyl)phenyl]-7-phenoxyindolizin-3-yl}ethanone (GSK2847449A)
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Categories: Homo sapiens | Arrowsmith, C H | Bountra, C | Chaikuad, A | Chen, P | Chung, C W | Delft, F von | Drewry, D | Edwards, A M | Fedorov, O | Felletar, I | Filippakopoulos, P | Knapp, S | Krojer, T | Structural genomic | Acetylated lysine binding protein | Bromodomain | Kiaa1476 | Sgc | Transcription | Walp4
