2a2t

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[[Image:2a2t.gif|left|200px]]<br /><applet load="2a2t" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2a2t.gif|left|200px]]
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caption="2a2t, resolution 3.10&Aring;" />
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'''crystal structure of d(AAATATTT)'''<br />
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{{Structure
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|PDB= 2a2t |SIZE=350|CAPTION= <scene name='initialview01'>2a2t</scene>, resolution 3.10&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=CAC:CACODYLATE ION'>CAC</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''crystal structure of d(AAATATTT)'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2A2T is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=CAC:'>CAC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A2T OCA].
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2A2T is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A2T OCA].
==Reference==
==Reference==
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Structure of a DNA duplex with all-AT base pairs., Valls N, Richter M, Subirana JA, Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1587-93. Epub 2005, Nov 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16301792 16301792]
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Structure of a DNA duplex with all-AT base pairs., Valls N, Richter M, Subirana JA, Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1587-93. Epub 2005, Nov 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16301792 16301792]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Richter, M.]]
[[Category: Richter, M.]]
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[[Category: mn]]
[[Category: mn]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:23:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:44:40 2008''

Revision as of 13:44, 20 March 2008

Image:2a2t.gif


PDB ID 2a2t

Drag the structure with the mouse to rotate
, resolution 3.10Å
Ligands: and
Coordinates: save as pdb, mmCIF, xml



crystal structure of d(AAATATTT)


Overview

The structure of the oligonucleotide duplex d(AAATATTT)(2) has been obtained in two crystal forms. In both cases the duplexes show Watson-Crick base pairs and are organized as a helical arrangement of stacked oligonucleotides. The helices contain either 11 duplexes in seven turns (form I) or 14 duplexes in nine turns (form II). As a result, the crystals have rather large unit cells. Such an organization of DNA duplexes has not been previously described in oligonucleotide crystal structures. The columns of stacked duplexes are organized in a pseudohexagonal arrangement. They do not show any direct lateral interactions; instead, these are indirectly mediated by shared and disordered hydrated ions. Such interactions are similar to those found in DNA fibres. The structural parameters of the individual base steps coincide with those found in other structures which contain CG terminal base pairs.

About this Structure

2A2T is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Structure of a DNA duplex with all-AT base pairs., Valls N, Richter M, Subirana JA, Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1587-93. Epub 2005, Nov 19. PMID:16301792

Page seeded by OCA on Thu Mar 20 15:44:40 2008

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