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4dtz
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4dtz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DTZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DTZ FirstGlance]. <br> | <table><tr><td colspan='2'>[[4dtz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DTZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DTZ FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=LDP:L-DOPAMINE'>LDP</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=LDP:L-DOPAMINE'>LDP</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dsw|4dsw]], [[4dtw|4dtw]], [[4dty|4dty]], [[4du2|4du2]], [[4dua|4dua]], [[4dub|4dub]], [[4duc|4duc]], [[4dud|4dud]], [[4due|4due]], [[4duf|4duf]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dsw|4dsw]], [[4dtw|4dtw]], [[4dty|4dty]], [[4du2|4du2]], [[4dua|4dua]], [[4dub|4dub]], [[4duc|4duc]], [[4dud|4dud]], [[4due|4due]], [[4duf|4duf]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYP102A1, cyp102 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1404 Bacillus megaterium])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYP102A1, cyp102 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1404 Bacillus megaterium])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dtz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dtz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dtz RCSB], [http://www.ebi.ac.uk/pdbsum/4dtz PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dtz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dtz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dtz RCSB], [http://www.ebi.ac.uk/pdbsum/4dtz PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CPXB_BACME CPXB_BACME]] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Bacillus megaterium]] | [[Category: Bacillus megaterium]] | ||
[[Category: Unspecific monooxygenase]] | [[Category: Unspecific monooxygenase]] | ||
| - | [[Category: Arnold, F H | + | [[Category: Arnold, F H]] |
| - | [[Category: Brustad, E M | + | [[Category: Brustad, E M]] |
| - | [[Category: Crook, N | + | [[Category: Crook, N]] |
| - | [[Category: Jasanoff, A | + | [[Category: Jasanoff, A]] |
| - | [[Category: Lelyveld, V S | + | [[Category: Lelyveld, V S]] |
| - | [[Category: Martinez, F M | + | [[Category: Martinez, F M]] |
| - | [[Category: Scholl, T J | + | [[Category: Scholl, T J]] |
| - | [[Category: Snow, C D | + | [[Category: Snow, C D]] |
[[Category: Cytochrome p450]] | [[Category: Cytochrome p450]] | ||
[[Category: Directed evolution]] | [[Category: Directed evolution]] | ||
[[Category: Mri contrast sensor]] | [[Category: Mri contrast sensor]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 22:50, 24 December 2014
cytochrome P450 BM3h-8C8 MRI sensor bound to dopamine
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