We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
4hbq
From Proteopedia
(Difference between revisions)
| Line 8: | Line 8: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hbq RCSB], [http://www.ebi.ac.uk/pdbsum/4hbq PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hbq RCSB], [http://www.ebi.ac.uk/pdbsum/4hbq PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MADCA_HUMAN MADCA_HUMAN]] Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 22:53, 24 December 2014
Crystal structure of a loop deleted mutant of Human MAdCAM-1 D1D2
| |||||||||||
