4pqa
From Proteopedia
(Difference between revisions)
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<StructureSection load='4pqa' size='340' side='right' caption='[[4pqa]], [[Resolution|resolution]] 1.78Å' scene=''> | <StructureSection load='4pqa' size='340' side='right' caption='[[4pqa]], [[Resolution|resolution]] 1.78Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4pqa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PQA OCA]. <br> | + | <table><tr><td colspan='2'>[[4pqa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Neimb Neimb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PQA FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=X8Z:L-CAPTOPRIL'>X8Z</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=X8Z:L-CAPTOPRIL'>X8Z</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dapE, NMB1530 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=122586 NEIMB])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pqa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pqa RCSB], [http://www.ebi.ac.uk/pdbsum/4pqa PDBsum]</span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Succinyl-diaminopimelate_desuccinylase Succinyl-diaminopimelate desuccinylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.18 3.5.1.18] </span></td></tr> |
| - | <table> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pqa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pqa RCSB], [http://www.ebi.ac.uk/pdbsum/4pqa PDBsum]</span></td></tr> |
| - | == | + | </table> |
| - | + | == Function == | |
| + | [[http://www.uniprot.org/uniprot/DAPE_NEIMB DAPE_NEIMB]] Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity).[HAMAP-Rule:MF_01690] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Neimb]] | ||
[[Category: Succinyl-diaminopimelate desuccinylase]] | [[Category: Succinyl-diaminopimelate desuccinylase]] | ||
| - | [[Category: Anderson, W F | + | [[Category: Anderson, W F]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Holz, R | + | [[Category: Holz, R]] |
| - | [[Category: Joachimiak, A | + | [[Category: Joachimiak, A]] |
| - | [[Category: Nocek, B | + | [[Category: Nocek, B]] |
| - | [[Category: Starus ,A | + | [[Category: Starus ,A]] |
[[Category: Captopril]] | [[Category: Captopril]] | ||
| - | [[Category: Center for structural genomics of infectious disease]] | ||
[[Category: Csgid]] | [[Category: Csgid]] | ||
[[Category: Dape]] | [[Category: Dape]] | ||
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[[Category: National institute of allergy and infectious disease]] | [[Category: National institute of allergy and infectious disease]] | ||
[[Category: Niaid]] | [[Category: Niaid]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 22:56, 24 December 2014
Crystal Structure of succinyl-diaminopimelate desuccinylase from Neisseria meningitidis MC58 in complex with the Inhibitor Captopril
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Categories: Neimb | Succinyl-diaminopimelate desuccinylase | Anderson, W F | Structural genomic | Holz, R | Joachimiak, A | Nocek, B | Starus ,A | Captopril | Csgid | Dape | Hydrolase | Hydrolase-hydrolase inhibitor complex | M20 aminopeptidase | Metaloenzyme | National institute of allergy and infectious disease | Niaid
