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4mpg
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target EFI-507257== | |
| - | + | <StructureSection load='4mpg' size='340' side='right' caption='[[4mpg]], [[Resolution|resolution]] 1.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | ==Function== | + | <table><tr><td colspan='2'>[[4mpg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MPG FirstGlance]. <br> |
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mpf|4mpf]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GSTT2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mpg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mpg RCSB], [http://www.ebi.ac.uk/pdbsum/4mpg PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/GST2_HUMAN GST2_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. | [[http://www.uniprot.org/uniprot/GST2_HUMAN GST2_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Glutathione S-transferase|Glutathione S-transferase]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Glutathione transferase]] | [[Category: Glutathione transferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Almo, S C | + | [[Category: Almo, S C]] |
| - | [[Category: Armstrong, R N | + | [[Category: Armstrong, R N]] |
| - | [[Category: Bhosle, R | + | [[Category: Bhosle, R]] |
| - | [[Category: Chowdhury, S | + | [[Category: Chowdhury, S]] |
| - | [[Category: EFI, Enzyme Function Initiative | + | [[Category: EFI, Enzyme Function Initiative]] |
| - | [[Category: Evans, B | + | [[Category: Evans, B]] |
| - | [[Category: Gerlt, J A | + | [[Category: Gerlt, J A]] |
| - | [[Category: Glenn, A Scott | + | [[Category: Glenn, A Scott]] |
| - | [[Category: Hammonds, J | + | [[Category: Hammonds, J]] |
| - | [[Category: Hillerich, B | + | [[Category: Hillerich, B]] |
| - | [[Category: Imker, H J | + | [[Category: Imker, H J]] |
| - | [[Category: Love, J | + | [[Category: Love, J]] |
| - | [[Category: Obaidi, N Al | + | [[Category: Obaidi, N Al]] |
| - | [[Category: Patskovsky, Y | + | [[Category: Patskovsky, Y]] |
| - | [[Category: Seidel, R D | + | [[Category: Seidel, R D]] |
| - | [[Category: Stead, M | + | [[Category: Stead, M]] |
| - | [[Category: Toro, R | + | [[Category: Toro, R]] |
| - | [[Category: Washington, E | + | [[Category: Washington, E]] |
[[Category: Efi]] | [[Category: Efi]] | ||
[[Category: Enzyme function initiative]] | [[Category: Enzyme function initiative]] | ||
Revision as of 23:11, 24 December 2014
Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target EFI-507257
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Categories: Glutathione transferase | Homo sapiens | Almo, S C | Armstrong, R N | Bhosle, R | Chowdhury, S | EFI, Enzyme Function Initiative | Evans, B | Gerlt, J A | Glenn, A Scott | Hammonds, J | Hillerich, B | Imker, H J | Love, J | Obaidi, N Al | Patskovsky, Y | Seidel, R D | Stead, M | Toro, R | Washington, E | Efi | Enzyme function initiative | Glutathione s-transferase | Structural genomic | Transferase
