1ni2
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ni2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NI2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NI2 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1ni2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NI2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NI2 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VIL2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VIL2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ni2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ni2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ni2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ni2 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ni2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ni2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ni2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ni2 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/EZRI_HUMAN EZRI_HUMAN]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.<ref>PMID:17881735</ref> <ref>PMID:18270268</ref> <ref>PMID:19111582</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Bretscher, A P | + | [[Category: Bretscher, A P]] |
| - | [[Category: Cerione, R A | + | [[Category: Cerione, R A]] |
| - | [[Category: Karplus, P A | + | [[Category: Karplus, P A]] |
| - | [[Category: Nassar, N | + | [[Category: Nassar, N]] |
| - | [[Category: Smith, W J | + | [[Category: Smith, W J]] |
[[Category: Acyl-coa-like domain]] | [[Category: Acyl-coa-like domain]] | ||
[[Category: Ferm]] | [[Category: Ferm]] | ||
Revision as of 23:20, 24 December 2014
Structure of the active FERM domain of Ezrin
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