3shi
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3shi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3shi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3shi RCSB], [http://www.ebi.ac.uk/pdbsum/3shi PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3shi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3shi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3shi RCSB], [http://www.ebi.ac.uk/pdbsum/3shi PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MMP1_HUMAN MMP1_HUMAN]] Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.<ref>PMID:1645757</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 23:21, 24 December 2014
Crystal structure of human MMP1 catalytic domain at 2.2 A resolution
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Categories: Homo sapiens | Interstitial collagenase | Bertini, I | Calderone, V | Cerofolini, L | Fragai, M | Geraldes, C F.G C | Hermann, P | Luchinat, C | Parigi, G | Teixeira, J | Hydrolase | Lanthanide | Matrix metalloproteinase | Paramagnetic restraint | Paramagnetic tag | Protein refinement | Residual dipolar coupling
