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1tfh
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1tfh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TFH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TFH FirstGlance]. <br> | <table><tr><td colspan='2'>[[1tfh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TFH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TFH FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HUMAN TISSUE FACTOR EXTRACELLU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HUMAN TISSUE FACTOR EXTRACELLU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tfh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tfh RCSB], [http://www.ebi.ac.uk/pdbsum/1tfh PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tfh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tfh RCSB], [http://www.ebi.ac.uk/pdbsum/1tfh PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TF_HUMAN TF_HUMAN]] Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.<ref>PMID:12652293</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Edgington, T S | + | [[Category: Edgington, T S]] |
| - | [[Category: Huang, M | + | [[Category: Huang, M]] |
| - | [[Category: Ruf, W | + | [[Category: Ruf, W]] |
| - | [[Category: Stefanko, R S | + | [[Category: Stefanko, R S]] |
| - | [[Category: Stone, M J | + | [[Category: Stone, M J]] |
| - | [[Category: Stura, E A | + | [[Category: Stura, E A]] |
| - | [[Category: Syed, R | + | [[Category: Syed, R]] |
| - | [[Category: Wilson, I A | + | [[Category: Wilson, I A]] |
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Coagulation factor]] | [[Category: Coagulation factor]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
[[Category: Tissue factor]] | [[Category: Tissue factor]] | ||
Revision as of 23:43, 24 December 2014
EXTRACELLULAR DOMAIN OF HUMAN TISSUE FACTOR
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