1ocp
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ocp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OCP FirstGlance]. <br> | <table><tr><td colspan='2'>[[1ocp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OCP FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">T7 GENE 1 UNDER CONTROL OF THE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">T7 GENE 1 UNDER CONTROL OF THE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ocp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ocp RCSB], [http://www.ebi.ac.uk/pdbsum/1ocp PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ocp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ocp RCSB], [http://www.ebi.ac.uk/pdbsum/1ocp PDBsum]</span></td></tr> |
- | <table> | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/PO5F1_MOUSE PO5F1_MOUSE]] Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.<ref>PMID:17496161</ref> <ref>PMID:17525163</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
- | [[Category: Hayashi, F | + | [[Category: Hayashi, F]] |
- | [[Category: Kyogoku, Y | + | [[Category: Kyogoku, Y]] |
- | [[Category: Morita, E H | + | [[Category: Morita, E H]] |
- | [[Category: Shirakawa, M | + | [[Category: Shirakawa, M]] |
[[Category: Dna-binding protein]] | [[Category: Dna-binding protein]] |
Revision as of 23:51, 24 December 2014
SOLUTION STRUCTURE OF OCT3 POU-HOMEODOMAIN
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