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2aex

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[[Image:2aex.gif|left|200px]]<br /><applet load="2aex" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2aex.gif|left|200px]]
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caption="2aex, resolution 1.58&Aring;" />
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'''The 1.58A Crystal Structure of Human Coproporphyrinogen Oxidase Reveals the Structural Basis of Hereditary Coproporphyria'''<br />
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{{Structure
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|PDB= 2aex |SIZE=350|CAPTION= <scene name='initialview01'>2aex</scene>, resolution 1.58&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=CIT:CITRIC ACID'>CIT</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Coproporphyrinogen_oxidase Coproporphyrinogen oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.3 1.3.3.3]
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|GENE= CPOX, CPO, CPX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''The 1.58A Crystal Structure of Human Coproporphyrinogen Oxidase Reveals the Structural Basis of Hereditary Coproporphyria'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2AEX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CIT:'>CIT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Coproporphyrinogen_oxidase Coproporphyrinogen oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.3 1.3.3.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AEX OCA].
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2AEX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AEX OCA].
[[Category: Coproporphyrinogen oxidase]]
[[Category: Coproporphyrinogen oxidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Raman, C S.]]
[[Category: Raman, C S.]]
[[Category: CIT]]
[[Category: CIT]]
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[[Category: flat beta-sheet sandwiched by helices]]
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[[Category: flat beta-sheet sandwiched by helice]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:26:41 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:48:48 2008''

Revision as of 13:48, 20 March 2008


PDB ID 2aex

Drag the structure with the mouse to rotate
, resolution 1.58Å
Ligands:
Gene: CPOX, CPO, CPX (Homo sapiens)
Activity: Coproporphyrinogen oxidase, with EC number 1.3.3.3
Coordinates: save as pdb, mmCIF, xml



The 1.58A Crystal Structure of Human Coproporphyrinogen Oxidase Reveals the Structural Basis of Hereditary Coproporphyria


Disease

Known diseases associated with this structure: Chondrodysplasia punctata, X-linked dominant OMIM:[300205], Cleft palate with ankyloglossia OMIM:[300307], Coproporphyria OMIM:[121300], Harderoporphyrinuria OMIM:[121300]

About this Structure

2AEX is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 15:48:48 2008

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