3ihy
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ihy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ihy RCSB], [http://www.ebi.ac.uk/pdbsum/3ihy PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ihy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ihy RCSB], [http://www.ebi.ac.uk/pdbsum/3ihy PDBsum]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/PK3C3_HUMAN PK3C3_HUMAN]] Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.<ref>PMID:7628435</ref> <ref>PMID:14617358</ref> <ref>PMID:20208530</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]] | *[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]] | ||
+ | == References == | ||
+ | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> |
Revision as of 00:09, 25 December 2014
Human PIK3C3 crystal structure
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Categories: Homo sapiens | Phosphatidylinositol 3-kinase | Arrowsmith, C H | Berg, S Van Den | Berglund, H | Bountra, C | Collins, R | Edwards, A M | Flodin, S | Flores, A | Graslund, S | Hammarstrom, M | Johansson, A | Johansson, I | Karlberg,T | Kotenyova, T | Kotzsch, A | Moche, M | Nielsen, T Kragh | Nordlund, P | Nyman, T | Persson, C | Roos, A K | Structural genomic | Sagemark, J | Schueler, H | Schutz, P | Siponen, M I | Thorsell, A G | Tresaugues, L | Weigelt, J | Welin, M | Wisniewska, M | Alpha/beta protein | Atp-binding | Kinase | Manganese | Nucleotide-binding | Phosphoprotein | Sgc | Sgc stockholm | Transferase