2yek

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yek OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yek RCSB], [http://www.ebi.ac.uk/pdbsum/2yek PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yek OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yek RCSB], [http://www.ebi.ac.uk/pdbsum/2yek PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN]] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Chung, C W.]]
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[[Category: Chung, C W]]
[[Category: Epigenetic reader]]
[[Category: Epigenetic reader]]
[[Category: Histone]]
[[Category: Histone]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]

Revision as of 00:14, 25 December 2014

Crystal Structure of the First Bromodomain of Human Brd2 with the inhibitor GSK525762 (IBET)

2yek, resolution 1.98Å

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