2zqe

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZQE FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZQE FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA1645 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA1645 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zqe RCSB], [http://www.ebi.ac.uk/pdbsum/2zqe PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zqe RCSB], [http://www.ebi.ac.uk/pdbsum/2zqe PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q5SHT5_THET8 Q5SHT5_THET8]] Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Cleaves the phosphate backbone of oligodeoxynucleotides non-sequence-specifically at the 3' side of the phosphates. Preferably incises the branched DNA structures, especially the D-loop structure over the Holliday junction. Has ATPase activity. Binds to dsDNA but not to ssDNA.<ref>PMID:15113836</ref> <ref>PMID:17215294</ref> <ref>PMID:17686785</ref> <ref>PMID:18838375</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Fukui, K.]]
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[[Category: Fukui, K]]
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[[Category: Kitamura, Y.]]
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[[Category: Kitamura, Y]]
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[[Category: Kuramitsu, S.]]
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[[Category: Kuramitsu, S]]
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[[Category: Masui, R.]]
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[[Category: Masui, R]]
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[[Category: Nakagawa, N.]]
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[[Category: Nakagawa, N]]
[[Category: Alpha/beta]]
[[Category: Alpha/beta]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]

Revision as of 00:15, 25 December 2014

Crystal structure of the Smr domain of Thermus thermophilus MutS2

2zqe, resolution 1.70Å

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