4ra8

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m (Protected "4ra8" [edit=sysop:move=sysop])
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ra8]] is a 5 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3tn1 3tn1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RA8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ra8]] is a 5 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3tn1 3tn1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RA8 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ra8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ra8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ra8 RCSB], [http://www.ebi.ac.uk/pdbsum/4ra8 PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ra8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ra8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ra8 RCSB], [http://www.ebi.ac.uk/pdbsum/4ra8 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CCL3_HUMAN CCL3_HUMAN]] Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).<ref>PMID:8525373</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Guo, Q.]]
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[[Category: Guo, Q]]
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[[Category: Liang, W G.]]
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[[Category: Liang, W G]]
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[[Category: Ren, M.]]
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[[Category: Ren, M]]
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[[Category: Tang, W J.]]
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[[Category: Tang, W J]]
[[Category: Cytokine]]
[[Category: Cytokine]]

Revision as of 00:18, 25 December 2014

Structure analysis of the Mip1a P8A mutant

4ra8, resolution 2.60Å

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